Application Development

I need an application that performs like a spreadsheet. There will be roughly 25 inputs and after the inputs are made, I want to be able to push a "calcuate" button and have roughly 75 outputs. There will be about 12 pages of information based on the outputs including graphs, illustrations, pictures and other descriptors of the outputs. These pages will need to have a design component because this will be a point of sale piece. An application written in Excel would be acceptable. I want the flexibility of a stand alone windows application with the possibility of changing the inputs to access from the web. The outputs would preferably be in PDF. See attached.