Set Up Calling Outbound and Inbound calling from Twilio

I have a trial Twilio account with phone number. I want to set up OUTGOING and INCOMING calls and take it live. That's the project. Really simple. Phase 1: For this project tell me 1) What you need in place to begin (Technical) and 2) How long to complete. There may be ongoing work like CRM integration as well after PHASE 1.